Array comparative genomic hybridization analysis of olfactory neuroblastoma
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چکیده
منابع مشابه
Computational Methods for the Analysis of Array Comparative Genomic Hybridization
Array comparative genomic hybridization (array CGH) is a technique for assaying the copy number status of cancer genomes. The widespread use of this technology has lead to a rapid accumulation of high throughput data, which in turn has prompted the development of computational strategies for the analysis of array CGH data. Here we explain the principles behind array image processing, data visua...
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BACKGROUND Male infertility caused by a maturation arrest of spermatogenesis is a condition with an abrupt stop in spermatogenesis, mostly at the level of primary spermatocytes. The etiology remains largely unknown. METHODS We focused on patients with a complete arrest at the spermatocyte level (n = 9) and used array comparative genomic hybridization to screen for deletions or duplications th...
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In this study, we performed high-resolution array comparative genomic hybridization with an array of 4153 bacterial artificial chromosome clones to assess copy number changes in 44 archival breast cancers. The tumors were flow sorted to exclude non-tumor DNA and increase our ability to detect gene copy number changes. In these tumors, losses were more frequent than gains, and gains in 1q and lo...
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We read with interest the article by Baldwin et al. (1), which describes the use of an array of 32,433 bacterial artificial chromosome clones tiled across the genome (2, 3) to map genomic aberrations in 20 oral squamous cell carcinoma samples by array comparative genomic hybridization (array CGH). The authors conclude that improved detection sensitivity and resolution of tiling arrays is necess...
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ژورنال
عنوان ژورنال: Modern Pathology
سال: 2008
ISSN: 0893-3952,1530-0285
DOI: 10.1038/modpathol.2008.57